Aging brain reduces ovulation
Contact: Sonja Jacobs newsnwo.nl 31-70-344-0713 Netherlands Organization for Scientific Research Franke Annelieke Dutch researcher has discovered that the aging of the brain affects the fertility of female rats. The scientist suspects that her research insight into the problems of fertility of women over 30 years. Franke studied relatively young subfertile mice. Although the pituitary gland and the ovaries of mice was normal, his brain had already started to work differently.Franke This led to the conclusion that the aging of the brain reduces fertility.In general, the human brain regulate the reproductive system in the same way that the brain of rats. However, one important difference is that the rats still possess a considerable number of oocytes after the fertile period
in humans decimated the supply considerably. This reduction in supply of eggs is the main limiting factor for fertility in older women. Despite these differences between humans and rats, researchers are still hoping that the aging brain in humans also has a role in reducing fertility through the ages.This knowledge can help develop treatments for relatively young women who are subfertile. Womens fertility decreases after age 30 and older. This can be problematic for women who desire a career before having children. Ovulation of oocytes is one of the factors that reproduction is regulated by the brain. An opening signal of the brain indicates the pituitary gland to produce more luteinizing hormone (LH). A feedback mechanism from the ovaries to the brain ensures that
ovulation occurs only when the follicles and mature oocytes.The follicles produce large amounts of estrogen. The brain responds to these questions and ovulation begins.Researchers have shown that this feedback mechanism does not work optimally in old female rats. Although estrogen levels in the blood does not change with age, fewer receptors for estrogen and progesterone, were in some areas of the brain. Furthermore,
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