Antibiotics alter GI tract microbes and increase lung sensitivity to allergens
Allergies before the hard life? Tired of popping antihistamines like candy? Can not go anywhere without your inhaler? The real problem is not filled his head up. It could be the microbes in the gut. At the American Society for Microbiology meeting held here this week, the scientists at the University of Michigan Medical School, the results of experiments with laboratory mice indicating that antibiotic-induced changes can affect the microbes in the stomach present tract, the immune system responds to common allergens in the lungs.We all have a unique microbial fingerprint of a specific mixture of bacteria and fungi that live in our stomach and intestines, said Gary B. Huffnagle, Ph.D., associate professor of internal medicine and microbiology and immunology at the UM
Medical School. Antibiotics knock out bacteria in the intestine, so that fungi take over temporarily until the bacteria grow back after the antibiotics are stopped. Our research shows that the change of intestinal microflora this way can lead to changes of the entire immune system, may produce symptoms elsewhere in the body.If confirmed in human clinical studies, Huffnagle believes his findings may help explain why cases of chronic inflammatory diseases such as asthma and allergies have increased rapidly over the past 40 years, a period that corresponds to the use Widespread use of antibiotics. To understand the implications of the UM research, it is important to know something about the complex relationship between the digestive system, respiratory and immune systems in
humans. Each time you inhale, air flows past the mucus-producing cells and tiny hairs designed to trap bits of pollen, dust and spores before they enter the lungs.These trapped particles are swept into the stomach with saliva and mucus as a dove.Anything you inhale, swallow, too, Huffnagle said. Thus, the immune cells in the gastrointestinal tract are exposed directly to airborne allergens and particulates. This triggers
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