Beta-blockers in heart failure patients tolerated
Treatment with beta-blockers in patients with heart failure is well tolerated and with less total withdrawals heart failure and less deterioration than placebo, according to an article in the July 12th edition of Archives of Internal Medicine, one of the journals JAMA / Archives journals. Beta blockers are a class of drugs that adrenergic beta-blocking stress on the heart, slow heart rate, reduce the force with which contracts the heart and reduce blood vessel contraction in the heart, brain and the body.According to the information in this article, beta-blockers significantly improve survival in patients with chronic heart failure (HF) with left ventricular systolic dysfunction (left ventricular failure to comply with the contract with enough force to pump blood to the
body). But concerns about cardiovascular side effects, doctors can prescribe this therapy to discourage. Dennis T. Ko, MD, University of Toronto, Ontario, Harlan Krumholz, MD, led by Yale University School of Medicine and his colleagues an overview of randomized trials that compared to placebo, beta-blockers in patients with heart failure quantify the risks side effects.The tests were identified by electronic searches of MEDLINE from 1966 to 2002. Nine studies involving 14 594 patients with follow-up of six to 24 months were included in the program. Although therapy with beta-blockers with hypotension [low blood pressure], dizziness and bradycardia [slow heart beat], has been linked to the absolute increase in risk was low and, in general, patients n were not treated with
beta-blockers be withdrawn from the placebo, the authors. Leave a beta-blocker therapy was associated with a significant reduction of 27 percent from all-cause mortality and absolute risk reduction of 34 deaths per 1,000 patients per year.E was associated with significant absolute annual increases in risks of hypotension (11 per 1,000), dizziness (57 per 1,000) and bradycardia (38 per 1,000). E was associated with a reduction Pages: [1] 2 3